Anticorrosive, antihydrogenating and bactericidal effects of a number of expired drugs

• L.E. Tsygankova and V.A. Kur’yato

Derzhavin State University, 33 Internatsionalnaya St., 392000 Tambov, Russia

Abstract: The article evaluates the anticorrosive and antihydrogenation effects of expired drugs Omeprazole, Drotaverine and Anaprilin in relation to the corrosion of St3 steel in 1 N solutions of HCl and H₂SO₄, as well as the bactericidal effect in relation to sulfate-reducing bacteria (SRB). The protective effect of drugs in a concentration of 40–80 mg/L was assessed at room temperature and 80°C using a gravimetric method, and the possibility of its increasing was shown by combining the drugs with Urotropine in HCl solutions and with KCNS in H₂SO₄ solutions. With the combined presence of the drugs and additives, an increase in the protective effect was observed in both environments at room temperature. At 80°C, only the combination of Drotaverine with KCNS in 1 N H₂SO₄ was shown to have a value of Z>90%. Analysis of polarization curves in the environments under study showed that the protective efficiency of the drugs and their compositions with Urotropine and KCNS is due to their effect on slowing down the partial electrode reactions on the steel electrode. Using the electrochemical diffusion method, it was shown that the drugs studied slow down the diffusion of hydrogen into metal in HCl and H₂SO₄ solutions. Omeprazole and Drotaverine were shown to have a bacteriostatic effect on SRB in Postgate B nutrient medium, inhibiting the growth of their cells and the production of hydrogen sulfide.

Keywords: steel, corrosion, protection, hydrogenation, bactericidal action, SRB, Omeprazole, Drotaverine, Anaprilin, Urotropine, KCNS, polarization

Int. J. Corros. Scale Inhib., 2025, 14, no. 4, 1832-1846
doi: 10.17675/2305-6894-2025-14-4-6

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